AMTの製造にはいくつかの技術的な課題があり、主に以下の点に注意する必要があります：
- 純度の管理： タングステン鉱にはモリブデン（Mo）が含まれていることが多く、モリブデンはタングステンと化学的に似ており、完全に分離することが困難です。産業では、モリブデンを除去するために複数回の結晶化や選択的沈殿を使用しますが、これにはコストが増加します。
- 結晶化プロセスの安定性： 溶液の濃度、温度、攪拌速度がわずかに変動するだけで、結晶の粒径が均一でなくなり、後続の応用に影響を与えます。さらに、廃液の処理も大きな課題です。酸化法で生成されるアンモニアを含む廃水やイオン交換法での酸洗液は、環境規制に従って適切に処理する必要があります。
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