What impact do microstructural defects of tungsten alloy screws have on their performance? Defects like pores, cracks, and segregation significantly reduce mechanical and thermal performance. First, pore defects: density reduction 5%-10%, causing stress concentration, shortening fatigue life 30%, affecting fastening reliability. Second, crack defects: propagation leading to brittle fracture, tensile strength drop 20%-40%, accelerating creep at high temperatures. Third, segregation defects: uneven phase distribution, uneven hardness, corrosion rate increase 2 times, weakening radiation shielding. Fourth, dislocations and inclusions: increasing internal stress, reducing ductility, prone to loosening under vibration. Fifth, radiation-induced defects: hardening in nuclear applications, increasing brittleness. These impacts can be mitigated by optimizing sintering to reduce defects, enhancing performance.